Values of magnetic Resonance imaging and Cerebrospinal fluid analysis in the diagnosis of Central Nervous System associated infectious diseases
نویسنده
چکیده
Objective To discuss the roles of magnetic resonance imaging (MRI) and cerebrospinal fluid analysis in the identification of central nervous system associated infection and provide a reference for the diagnosis and treatment of central nervous system associated infectious diseases. Methods Seventy-six patients who developed central nervous system infection and were admitted into the Henan People's Hospital between June 2014 and October 2015 were randomly selected as an observation group. Patients in the observation group were subdivided according to purulent meningitis, cryptococcal meningitis, viral meningitis and tubercular meningitis. Moreover, 35 headache patients who were admitted in the same period were selected as a control group. The MRI results and cerebrospinal fluid examination indicators were compared between the two groups. Results MRI results suggested that the positive rate of the observation group was 96.05% (73/76), much higher than 8.57% in the control group (3/35), and the difference had statistical significance (P<0.05). The analysis results of cerebrospinal fluid demonstrated that the concentration of lactate dehydrogenase (LDH) in the cerebrospinal fluid of the patients with tubercular meningitis was the highest, the concentration of creatine kinase (CK) in the cerebrospinal fluid of the patients with purulent meningitis was the highest, and the concentration of lactic acid (LA) in the cerebrospinal fluid of the patients with tubercular meningitis and purulent meningitis was higher than that of the other patients; the differences were statistically significant (P<0.05). The analysis on the diagnostic efficacy of MRI in combination with cerebrospinal fluid analysis suggested that the sensitivity of the diagnostic scheme was high in diagnosing meningitis except purulent meningitis, and the specificity and accuracy of the scheme was high in diagnosing meningitis except cryptococcal meningitis. Conclusion MRI in combination with cerebrospinal fluid analysis is effective in diagnosing central nervous system associated infectious diseases. It can also effectively identify the types of infection besides improving accuracy, which provides an important reference for clinical treatment.
منابع مشابه
Diagnosis of Meningitis Caused by Pathogenic Microorganisms Using Magnetic Resonance Imaging: A Systematic Review
Introduction: Bacterial meningitis is an acute infectious inflammation of the protective membranes covering the brain. Its early diagnosis is vital because of its high morbidity and mortality. It is mostly diagnosed by a gold standard diagnostic tool i.e. Cerebrospinal Fluid (CSF) analysis. However, it is sometimes difficult and or impossible to do this procedure and an alternative diagnostic t...
متن کاملProgressive visual and hearing loss as looming manifestations of spinal meningeal melanocytoma
Abstract Meningeal melanocytoma is a rare tumor of nervous system, which originates from leptomeningeal melanocytes. The locations of melanocytoma in the nervous system are most frequently in the posterior fossa or along the spinal cord, and usually appear as an extra-axial mass. The manifestations of tumor are most often due to its compressing effect on adjacent nervous structures that c...
متن کاملEXTENDED REPORT Infectious CNS disease as a differential diagnosis in systemic rheumatic diseases: three case reports and a review of the literature
Background: Immunosuppressive treatment of rheumatic diseases may be associated with several opportunistic infections of the brain. The differentiation between primary central nervous system (CNS) involvement and CNS infection may be difficult, leading to delayed diagnosis. Objective: To differentiate between CNS involvement and CNS infection in systemic rheumatic diseases. Methods and results:...
متن کاملMagnetic Resonance Imaging of Central Nervous System and Paranasal Sinuses in Multiple Sclerosis Patients: Findings from a Survey of Clinical Records in Kermanshah Province
Background and Objectives: Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system with more than 5.2 million people across the world being afflicted with. Magnetic Resonance Imaging (MRI) is a valuable tool in the diagnosis of MS. This study surveys the results of MRI of the central nervous system and paranasal sinuses in the sample of MS patients in Ker...
متن کاملAnalysis of Cerebrospinal Fluid in Diagnosis of Bacterial Meningitis; Using Nuclear Magnetic Resonance Spectroscopy: A Systematic Review
Background: Analysis of biofluids provides a unique window into the biochemical status of a living organism since the composition of a given biofluid will be modulated according to the level of function of the cells that are intimately concerned with its manufacture and secretion. One of the most successful approaches to biofluid analysis has been the application of NMR spectroscopy. Objective...
متن کامل